Methods and systems for nondisruptive loading of reagents in a body fluid workstation

ABSTRACT

A method of nondisruptive loading of reagents in a body fluid workstation including a plurality of analyzers, including: receiving application information to a first analyzer which needs loading of a reagent; loading the reagent into the first analyzer; controlling the first analyzer to pause dispensing of the reagent at a determined time; and controlling one or more other analyzers in the body fluid workstation to continue testing, wherein controlling the one or more other analyzers includes adjusting a test sequence of one or more sample racks in the one or more other analyzers subsequent to the first analyzer, and dispatching the one or more sample racks according to the adjusted test sequence.

TECHNICAL FIELD

This disclosure relates to a body fluid workstation and, moreparticularly, to a body fluid workstation with multiple analyzers thatcan implement nondisruptive loading of reagents without shutting downone or more of the analyzers.

BACKGROUND

A biochemical analyzer is one common type of body fluid analyzer. Abiochemical analyzer may include a dispensing mechanism, a reagent disk,a sample disk, and a reaction disk. The sample disk is used for holdinga sample container that contains a sample for testing. The reagent diskis used for holding a reagent container that contains a reagent. Thereaction disk is used for holding a cuvette. By controlling the rotationof the reagent disk, the sample disk, and the reaction disk, adispensing mechanism dispenses sample and reagent into the cuvette.Testing and analysis are executed after the sample and reagent are mixedand reacted.

With the proliferation of body fluid analyzer applications and theincrease in the number of samples to be tested, integrated body fluidworkstations have appeared. These body fluid workstations may be usedfor biochemical analysis as biochemical analysis assembly lineworkstations. They may also be used for fluid analysis as body fluidworkstations for blood, serum, urine, or other body fluid testing. Suchbody fluid workstations may include two or more analyzers, each analyzerincluding a dispensing mechanism, a reagent disk, and a reaction disk.In addition, such body fluid workstations may adopt a unified conveyancetrack, which is used for conveying sample racks that hold samplecontainers for testing. The sample racks are conveyed to a determinedanalyzer for dispensing and testing by the track.

Body fluid workstations require a high degree of automation, fasttesting speeds, and the ability to process many samples. Becausehospitals process many samples at a given time, there are also manyreagents used in the testing process. In a fluid workstation, the doctorusually adds sufficient reagents at the beginning of a day so as tohandle one day's consumption.

Advantages of adding reagents in this way include that it is easy andconvenient for the doctor. However, there are also drawbacks. If aparticular reagent is exhausted during testing, the testing cannot bepaused, and the system must wait until other sample(s) have finishedtesting. Thereafter, the doctor must add more of the reagent that ranout and test the corresponding sample again, wasting the doctor's time.This may be of particular concern in emergency situations. If there isinsufficient reagent during testing, the analyzer must be stopped to addthe reagent, resulting in delayed reporting of test results.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 is a schematic diagram of an embodiment of a body fluidworkstation.

FIG. 2 is a flow chart of an embodiment of nondisruptive loading of areagent.

FIG. 3 is a flow chart of an embodiment of nondisruptive loading of areagent.

DETAILED DESCRIPTION

This disclosure includes systems and methods for operating a fluidworkstation including multiple analyzers and nondisruptively loadingreagents, i.e., reagents that can be loaded without shutting down one ormore of the analyzers, allowing them to continue testing. Utilizing thepresent disclosure, a user of a body fluid workstation can add reagentin one or more analyzers without influencing the other analyzers,thereby avoiding retesting a sample due to lack of a reagent, andstopping and restarting the workstation. This method will save time andensure the timely output of emergency test reports.

Referring to FIG. 1, a body fluid workstation includes a sample loadingmechanism and at least two analyzers. The illustrated embodimentincludes two analyzers, labeled M1 and M2. In other embodiments, theremay be three or more analyzers, and a sample loading mechanism mayinclude a sample loading track and a sample rack driving mechanism (notshown). The sample loading track may be used for holding a sample rackand restricting the moving track of the sample rack, the sample loadingtrack include the first track 6 and a second sample track 7.

The sample rack driving mechanism may be used for moving a sample rackto a determined place according to dispatching instructions. Forexample, the sample rack driving mechanism may be used for moving asample rack to a test position of one of the analyzers for testingaccording to the dispatching instructions. The sample rack drivingmechanism may be embodied, for example, as a transmission belt, aputter, or a push plate.

Each analyzer may include a dispensing mechanism, a reagent disk, and areaction disk. The reagent disk may be used for holding the reagentcontainer including reaction reagent, which is used for testing. Thereaction disk may be used for holding a cuvette. The analyzer maydispense samples and reagents for a sample rack, which is moved to thedetermined position, for example, by a sample dispensing mechanism. Thesample dispensing mechanism dispenses samples and reagents to thecuvette for testing.

According to one embodiment, if the system needs to pause testing of aparticular analyzer (e.g., M1 or M2) of the body fluid workstation, thesystem may ensure that the unaffected analyzer(s) continue to test. Asdescribed in greater detail below, according to the user's loadingapplication information, the system may decide, for example, to pausedispatching of a sample rack for an analyzer that needs nondisruptiveloading of one or more reagents. The sample rack of the otheranalyzer(s) may continue to dispatch.

In one embodiment, according to application information input by theuser, the loading system of the workstation will pause one analyzer at adetermined moment to allow nondisruptive loading of reagent(s), as wellas control the other analyzer(s) to allow testing to continue. Forexample, after the loading system receives loading applicationinformation, it controls the analyzer corresponding to the loadingapplication information to pause the dispensing operation. In anotherembodiment, after the loading system receives loading applicationinformation, according to the current test status of the analyzercorresponding to the loading application information, the system willdecide when to control the analyzer to pause the dispensing operation.When a user inputs loading application information, the loading systemchecks the test status of the analyzer which corresponds to the loadingapplication information when the analyzer is testing. It should bedetermined whether the analyzer corresponding to the loading applicationinformation meets the condition. When the analyzer meets the condition,it pauses the dispensing operation. When the user inputs conveyanceinstructions to the analyzer corresponding to the loading applicationinformation, the paused analyzer may continue to test.

In one embodiment, the loading system may also check the test items andtest sequence of each sample rack, determine whether a sample rack isthe first sample rack that the analyzer corresponding to the loadingapplication information is testing or will test, and, if it is, generatea dispatch construction of the first sample rack, such that the sampleloading mechanism will pause dispatch of the first sample rack accordingto dispatch construction. For example, the first sample rack may bepaused in the first sample loading track while sample racks of otheranalyzers continue to dispatch. A hot loading system can be made in oneor more integrated chips, or in separate hardware.

In one embodiment, the loading system of the body fluid workstationincludes an input unit, a testing unit, and a sample loading unit. Thefunctionality of various units may include steps, which may be embodiedin machine-executable instructions to be executed by a general-purposeor special-purpose computer (or other electronic device). Alternatively,the steps may be performed by hardware components that include specificlogic for performing the steps, or by a combination of hardware,software, and/or firmware.

The input unit is configured for receiving loading applicationinformation for the analyzer which needs nondisruptive loading of one ormore reagents. The application information is input by one or moreusers. The testing unit includes a pausing sub-unit configured forresponding to the loading application information, controlling theanalyzer corresponding to the loading application information to pausetesting, and controlling the other analyzer(s) of the body fluidworkstation to continue testing. The sample loading unit is configuredfor checking test items and the test sequence of each sample rack,determining whether a sample rack is the first sample rack to be testedby the analyzer corresponding to the loading application information. Ifit is, the sample loading unit will pause dispatching the first samplerack. The first sample rack is held in the sample loading track of theanalyzer corresponding to the loading application information whilewaiting to be tested, and the other analyzers continue to dispatch.

In other embodiments, the testing unit includes an adjustment sub-unit.The adjustment sub-unit is configured for adjusting the test sequence ofthe sample rack corresponding to the analyzer which comes after theanalyzer corresponding to the loading application information. Thesample loading unit may dispatch the sample rack according to thischanged sequence.

In another embodiment, the adjustment sub-unit includes a first checkunit and a test sequence change unit. The first check unit is configuredfor determining, after the first sample rack is tested by the analyzercorresponding to the loading application information, whether subsequentanalyzers of the body fluid workstation need to test that sample rack.The test sequence change unit is configured for changing the testsequence of the first sample rack in subsequent analyzers when the firstrack needs subsequent analyzers of body fluid workstation to test, thetest sequence of the first sample rack in subsequent analyzer isadjusted afterward. The sample loading unit dispatches the sample rackaccording to the adjusted test sequence. The second sample rack, whichis tested in the subsequent analyzer before the first sample rack, willbe conveyed to the test position of the subsequent analyzer by thesecond sample loading track, which is different from the first sampleloading track.

In one embodiment, the adjustment sub-unit includes a second check unitand test sequence change unit, the second check unit is configured formonitoring the test sequence of a sample rack on a sequence analyzer,which test sequence of the analyzer is corresponding to the loadingapplication information. When the first sample rack is going to betested, the adjustment sub-unit checks the test status of the firstsample rack in the analyzer corresponding to the loading applicationinformation. The test sequence change unit is configured for changingthe test sequence of the first sample rack in the subsequent analyzerwhen the test of the first sample rack is not finished in the analyzercorresponding to the loading application information, and to adjust thetest sequence of the first sample rack in the subsequent analyzersbackwards. The sample loading unit dispatches the sample rack accordingto the adjusted test sequence. After adjustment, the second sample rack,which tests in the subsequent analyzer before the first sample rack,will be conveyed to the test position of the subsequent analyzer by thesecond sample loading track, which is different from the first sampleloading track.

To control the residual reagent, the loading system also includes areagent loading unit and residual reagent calculation unit. The reagentloading unit is configured for acquiring parameters relating to liquidlevel detection and the test items. The residual reagent calculationunit is configured for calculating a test number of residual reagentsaccording to the parameters of the liquid level detection and testitems.

In order to inform users concerning the residual reagent, the loadingsystem also includes a reagent loading inform unit. The reagent loadinginform unit is configured for inputting the test number of each residualreagent to display and/or compare the test number of the residualreagent to the test number of the application. When the test number of aresidual reagent is less than the test number of the application, analarm and/or display of the reagent may be generated in a predeterminedmanner.

FIG. 2 shows a method of nondisruptively loading reagents. At Step S21,application information is received and input into the analyzer by auser. Utilizing a display interface, the user can decide whether tonondisruptively load a certain reagent and assign which analyzer to loadthe reagent into, and then can input the loading application informationof the analyzer via the interface.

At Step S22, the loading system responds to the application informationof the body fluid workstation and controls the first analyzercorresponding to the loading application information to pause adispensing operation. When pausing the dispensing operation of the firstanalyzer, the test status of the first analyzer could be considered, ornot be considered, according to various embodiments. For example, in oneembodiment, after receiving the loading application information, theloading system may control the first analyzer to pause dispensing of areagent immediately, without considering the test status of the firstanalyzer. In this situation, the reagent disk and the reagent dispensingmechanism pause operation, but the reaction disk, the sample disk, andthe sample dispensing mechanism may continue to work.

In another embodiment, after the loading system receives the loadingapplication information, it may control pausing of the dispensingoperation of the analyzer corresponding to the loading applicationinformation according to the test status of the analyzer, as follows:The loading system may acquire the test status of the first analyzer.When the first analyzer is testing, the system determines whether thefirst analyzer meets the pause condition. If it does not meet thecondition, the system causes the first analyzer to pause immediately.When the analyzer meets the condition, the system controls the firstanalyzer to pause the dispensing reagent operation. The pause conditioncould be, for example, that all reagents have been dispensed into acuvette to which a part of the reagents have been added. For example,when receiving loading application information, the first analyzer hasdispensed the first reagent to five cuvettes, but has not dispensed thesample and the other reagent. In this condition, to a single reagentitem, the loading system continues to control the pause operation of thereagent disk and the dispensing operation of the first analyzer.However, the reaction disk, the sample disk, and the sample dispensingmechanism continue to work, so as to finish the adding sample operation.To a multi-reagent item, the loading system continues dispensing sampleand the other reagent to the five cuvettes of the first analyzer. Afterdispensing the reagent to the five cuvettes, it then controls pausing ofthe dispensing operation of the first analyzer, so as to avoid reagentwaste or inaccurate test results.

At Step S23, the loading system controls the other analyzers of bodyfluid workstation to continue testing. After the loading system responseto the application information, the other analyzers of the workstationare not influenced. Thus, except for the first analyzer corresponding tothe loading application information, all analyzers continue to work.

At Step S24, the loading system dispatches the sample rack accordingly.The loading system acquires and checks the test item and the testsequence of each sample rack. The loading system determines whether asample rack is the first sample rack that the analyzer corresponding tothe application information is testing or will test. If so, the loadingsystem pauses the first sample rack dispatch. The first sample rack ispaused in the sample loading track and holds the first analyzer test,but allows the sample racks of the other analyzers to continuedispatching. After receiving the loading application information, thefirst sample rack is paused at the original position, waiting fortesting until the paused analyzer is restarted. The other analyzerscontinue to dispatch, allowing them to continue testing.

The sequence of Steps S22, S23, and S24 could be changed while realizingthe same effect.

In actual operation, the analyzer corresponding to the loadingapplication information could be the first analyzer along the sampleloading track, or could be positioned among analyzers, or could be thelast analyzer. The test sequence of a sample rack is usually based onthe order of the analyzers along the sample loading track; however,sample rack pass which analyzer is depend on test item and reagentplacement, the sample rack may not passes all analyzer. To the firstsample rack, it need pass the first analyzer, and also may need test byanalyzer which is after the first analyzer. When the first sample rackneed test by the subsequent analyzer which is after the first analyzer,the first sample rack is paused in the first analyzer because of loadingreagent hot, the first sample rack can not arrive at subsequent analyzeraccording to a predetermined time, this may cause subsequent analyzercan not test normally. And some sample rack may not need test by thefirst analyzer, but need test by subsequent analyzer, but the testsequence of the sample rack is after the first sample rack, if byoriginal dispatch way, it will cause unnecessarily wait and congestionof following sample rack.

In the present embodiment, by controlling each analyzer and dispatchingeach sample rack, controlling the first analyzer to pause whichcorresponds to the loading application information, the other,uninfluenced analyzer does not pause testing. Likewise, dispatching ofsample rack is paused which need testing by the first analyzer, whilethe other sample racks which do not need testing by the first analyzercontinue to be dispatched. The sample rack is conveyed to the testposition according to the test time, so that the other, uninfluencedanalyzer can test normally.

In order to ensure the accuracy of the test of the subsequent analyzer,when dispatching the other sample rack which does not need testing bythe first analyzer, the loading system changes the test sequence of thesample rack of the subsequent analyzer which is after the analyzercorresponding to loading application information. For example, itchanges the test sequence of the first sample rack in the subsequentanalyzer afterwards, and dispatches the sample rack according to theadjusted test sequence. The sample rack which is after the first samplerack is tested in the subsequent analyzer earlier than the first samplerack. Because the test sequence of the sample rack of subsequentanalyzer and dispatch way are changed at the same time, it is ensuredthat the test of subsequent analyzer is continuous and correct.

There are many ways to change test sequence of subsequent analyzer. Inone embodiment, the system may determine whether the first rack needstesting by the subsequent analyzer of the body fluid station after thefirst sample rack is tested by the analyzer corresponding to the loadingapplication information. If it is, the system changes the test sequenceof the first sample rack in subsequent analyzer, the test sequence ofthe first sample rack in the subsequent analyzer is adjusted afterward.In another embodiment, system real-time monitors the test sequence ofthe sample rack in subsequent analyzer which is after the analyzercorresponding to the loading application information, when the firstsample rack is going to be test (for example, there is some time orthere are several sample racks to test), checking the test status of thefirst sample rack in the analyzer corresponding to the loadingapplication information. If the test is not finished, the system changesthe test sequence of the first sample rack in subsequent analyzer,adjusting the test sequence of the first sample rack in subsequentanalyzer backwards. Adjusting the test sequence of sample rack insubsequent analyzer afterward, the system dispatches the sample rackaccording to the adjusted test sequence. The second sample rack whichtested in the subsequent analyzer before the first sample rack will beconveyed to the test position of the subsequent analyzer by the secondsample loading track, which is different from the first sample loadingtrack.

FIG. 3 illustrates a reagent loading method including the followingsteps.

In Step S30, the system collects user application information, a samplenumber, and a select item name of the application. The item ofapplication is the object for collection. Usually, user inputsapplication information of a sample. The application item of each samplemay not be the same. After the input work is finished, the user may notremember to apply how many times for each item.

In Step S31, according to application information input by step S30, thesystem collect the number of times for each item according to the itemname.

In Step S32, the system calculates a test number of residual reagent forevery item automatically, detects the reagent liquid height by liquiddetect device, acquires parameters of the liquid height detection andthe test item, then, calculates a test number of every residual reagentaccording to parameters of the liquid height detection and the testitem. When displaying the test number of every residual reagent, thetest number of every residual reagent of every analyzer can be displayon each analyzer, respectively, or the test number of every residualreagent of all analyzers is collected and display.

In step S33, the system may determine whether the residual reagent isenough, that is, determine whether the test number of the residualreagent is sufficient to meet the condition of nondisruptive loading thereagent. In one embodiment, the system may determine whether the testnumber of the residual reagent of every item meets the test number ofthe application. If the test number of the residual reagent is more thanthe test number of the application, the method may proceed to Step S34directly and dispatch the sample rack normally. However, if the testnumber of residual reagent is less than the test number of theapplication, the method may proceed to Step S35 directly and the systeminform the user to loading the reagent. In another embodiment, thesystem may determine whether the test number of each residual reagent isgreater than a determined threshold (e.g., 2 times). If it is, themethod may proceed to Step S24 to dispatch sample the rack normally. Ifnot, the system may inform the user to load the reagent.

In Step S35, the system may generate an alarm, for example, displayingthe reagent which needs to be loaded by color, flicker, or highlighting,or by alarm sounds, or display tips that point the user to which unit ofthe workstation need loading of the reagent. In other embodiment, thecomparison of Step S33 can be omitted. Instead, the system may displaythe test number of each residual reagent directly and constantlyupdated. The user may check and decide whether to load the reagentaccording to the test numbers of each residual reagent.

In Step S36, the user can decide whether to load the reagent accordingto the alarm, tips, etc. of Step S35, select the analyzer needingreagent(s) by man-machine interface, and input the loading applicationinformation. If there is only one analyzer that needs to load reagent,the user may select the only one analyzer to nondisruptive load reagent.If all of the analyzers need to load reagent(s), the user may select allof analyzers to nondisruptive load reagent. In certain circumstance,even if the user is informed about the need to load reagents in acertain analyzer, the user can also decide not to load the reagents bynot inputting the application information. For example, there is Xreagent on both the first analyzer and the second analyzer, when Xreagent of the first analyzer is going to be exhausted, and X reagentneeds to be loaded into the first analyzer, the user may decide to notinput application information to the first analyzer according to teststatus of sample rack and residual reagent of the second analyzer.Instead, when the second analyzer is also needed to load reagent X, theuser then inputs application information to one of the two analyzer orto both.

In Step S37, the testing unit will pause the test work of the analyzercorresponding to the loading application information while, at the sametime, keeping other analyzers which do not need to load reagents tocontinue to work. When the first sample rack also needs a subsequentanalyzer to test after pass the first analyzer corresponding to loadingapplication information, change test sequence of the first sample rackin the subsequent analyzer, adjust test sequence of the first samplerack in the subsequent analyzer backwards, so as to change test sequenceof sample rack in the subsequent analyzer. Alternatively, when the firstsample rack is going to be tested, the system may check the test statusof the first sample rack in the analyzer corresponding to the loadingapplication information. When the test of the first sample rack is notfinished, the system may adjust the test sequence of the first samplerack in the subsequent analyzer backwards, so as to change the testsequence of sample rack in the subsequent analyzer.

In Step S38, the sample loading unit will pause the dispatch of thesample rack in analyzer corresponding to the loading applicationinformation. The other analyzer will continue to dispatch normally. Thesample rack loading unit will check the test items and the test sequenceof each sample rack, determining whether the sample rack is the firstrack which is testing or going to be tested in the analyzercorresponding to the loading application information. If it is, thesystem pauses dispatch of the first sample rack and keeps other analyzergoing. If the test sequence sample rack in subsequent analyzer isadjusted, the system dispatches the sample rack according to theadjusted test sequence. After adjustment, the second sample rack may goto testing in a following sample rack earlier than the first sample rackis dispatched to the second sample loading track, which is differentfrom the first sample loading track. The system may control movement ofthe second sample rack to the test position of the subsequent analyzerby the second sample loading track.

In Step S39, after finishing the loading of reagent into the analyzer,in response to user input, the analyzer may restart and the test workmay continue, with the sample rack dispatching normally.

In certain embodiments, Step S37 and Step S38 can be exchanged, and thesequence of S37 and S38 can be changed.

Because the system is checking the residual reagent constantly accordingto the test application information input by the user, when determiningthat a certain residual reagent is not enough for adding in a certaincuvette, reagent should not be added to the cuvette. Therefore, isconvenient to control pausing the dispensing of reagent of the firstanalyzer. For example, after receiving application of the nondisruptiveloading, the test status of the first analyzer is testing, controllingthe first analyzer does not pause until all cuvettes which have reagentbeing added finished the dispensing reagent operation and do not need toconsider whether the residual reagent is insufficient

Referring again to FIG. 1, a body fluid workstation may include, as anexample, two analyzers, although three or more analyzers is similar.Along the direction of loading the sample, analyzer M2 is after analyzerM1, so M2 is the “subsequent” analyzer. The sample loading trackincludes the first sample loading track 6 and the second sample loadingtrack 7. There are test positions in the first sample loading track 6and the second sample loading track 7 corresponding to the analyzer M1and the analyzer M2 separately. Sample racks 1, 2, 3, 4, 5 are conveyedto the first sample loading track 6 and sample loading track 7 by thesample put area and the sample retrieve area 9. For example, a samplewhich needs to be tested by analyzer M1 will arrive at analyzer M1 andanalyzer M2 by the first sample loading track. Sample 1, 3, may onlyneed to tested by analyzer M2, and arrive at M2 directly by the secondsample loading track, e.g., sample racks 2, 5. After testing, the samplerack will be returned to the put area and the sample retrieve area 9.

When testing, if user finds analyzer M1 needs to load a reagent, theuser may selectively initiate a command to load the reagent to analyzerM1. After the analyzer M1 is selected to load the reagent, testing ofanalyzer M1 is paused. However, testing of analyzer M2 continues, andsample rack 3 needs to be tested by analyzer M1, so sample rack 3 ispaused in the first sample loading track 6. If the sample rack alsoneeds testing by analyzer M2, to avoid sample rack 3 having not yetarrived at the test position of analyzer M2, after the sample rack 1 andsample rack 2 are tested by the analyzer M2, it is needed to adjust thetest sequence of the sample rack in analyzer M2 and adjust the testsequence of sample rack 3 backwards, then dispatch the sample rackaccording to the adjusted test sequence of the sample rack. If samplerack 4 does not need test by analyzer M1, the test sequence of samplerack 4 will be adjusted in front of the sample rack 3. The sample rack 4may be driven by the sample rack driving device of sample loadingmechanism to the second sample loading track 7, and arrive at the testposition of analyzer M2 by the second sample loading track 7, or go tothe second sample loading track 7 initially, then be moved from thesecond sample loading track 7 to the first sample loading track 6, andpause in the test position of analyzer M2 in the first sample loadingtrack 6. If sample rack 4 is in the first sample loading track 6originally, then the sample rack 4 is conveyed to the second sampleloading track 7 initially, then arrives at the test position of analyzerM2 by the second sample loading track 7. If sample rack 4 also needstesting by analyzer M1, then sample rack 4 continues to wait for testingin the first sample loading track 6, and does not need to adjust thetest sequence of sample rack 5 in analyzer M2 in front of sample rack 3,and sample rack 5 is finished testing by analyzer M1, driving samplerack 5 to the second sample loading track 7 by the sample rack drivingdevice of the sample loading mechanism and arrives at test position ofanalyzer M2 by the second sample loading track 7.

In FIG. 1, the first sample loading track is closed to the analyzer. Inanother embodiment, the position of first sample loading track 6 and thesecond sample loading track 7 may be changed.

Those having skill in the art will appreciate that many changes may bemade to the details of the above-described embodiments without departingfrom the underlying principles of the invention. The scope of thepresent invention should, therefore, be determined only by the followingclaims.

What is claimed is:
 1. A method of nondisruptive loading of reagents ina body fluid workstation comprising a plurality of analyzers, including:receiving application information to a first analyzer which needsloading of a reagent; loading the reagent into the first analyzer;controlling the first analyzer to pause dispensing of the reagent at adetermined time; and controlling one or more other analyzers in the bodyfluid workstation to continue testing, wherein controlling the one ormore other analyzers comprises adjusting a test sequence of one or moresample racks in the one or more other analyzers subsequent to the firstanalyzer, and dispatching the one or more sample racks according to theadjusted test sequence.
 2. The method of claim 1, wherein controllingthe first analyzer comprises: when the first analyzer is testing,determining whether the first analyzer satisfies a pause condition; ifthe first analyzer meets the pause condition, controlling the firstanalyzer to pause dispensing the reagent.
 3. The method of claim 2,wherein the pause condition is met when all of needed reagents have beendispensed into a cuvette if part of the needed reagents have alreadybeen added into the cuvette.
 4. The method of claim 1, wherein, afterreceiving the application information, the method further includes asample rack dispatching step comprising: checking a test item performedon samples that are located in every sample rack and a test sequence ofevery sample rack; determining whether a sample rack is a first samplerack that the first analyzer is testing or will test; and if so, pausingdispatching of the first sample rack and allowing the one or more sampleracks tested on the one or more other analyzers to continue to dispatch.5. The method of claim 4, wherein adjusting the test sequence includes:determining whether the first sample rack also needs to be analyzed bythe one or more other analyzers of the body fluid workstation afterbeing tested by the first analyzer; if the first sample rack also needsto be analyzed by the one or more other analyzers, changing a testsequence of the first sample rack in a subsequent analyzer, the testsequence of the first sample rack in the subsequent analyzer is adjustedafterward.
 6. The method of claim 5, wherein dispatching the one or moreother sample racks according to the adjusted test sequence includes: ifa second sample rack is tested in the subsequent analyzer before thefirst sample rack is tested in the subsequent analyzer, the second rackis conveyed to a test position of the subsequent analyzer by a secondsample loading track which is different from a first sample loadingtrack for conveying the first sample rack.
 7. The method of claim 4,wherein adjusting the test sequence includes: monitoring a sequence ofsample racks in an analyzer subsequent to the first analyzer; when thesubsequent analyzer is going to test the first sample rack, checkingwhether the first analyzer is still testing; and if the first analyzeris still testing, changing a test sequence of the first sample rack inthe subsequent analyzer, wherein the test sequence of the first samplerack in the subsequent analyzer is adjusted afterward.
 8. The method ofclaim 1, wherein receiving application information of the first analyzeris preceded by: acquiring parameters of liquid height of reagents inevery analyzer and a test item performed on samples in every analyzer;calculating a test number for every residual reagent according to theparameters; outputting the test number that is performed with everyresidual reagent in every analyzer to a display; and determining whetherthe test number of every residual reagent meets a condition of loadingthe reagent, the condition of loading the reagent comprises that thetest number of the residual reagents is less than the test number of theapplication, and if the condition is met, notifying a user.
 9. Themethod of claim 1, wherein after the step of controlling the firstanalyzer to pause dispensing, the method includes: receiving aninstruction of restarting testing of the first analyzer; and controllingthe first analyzer to restart testing and dispatch sample racksnormally.
 10. A system for nondisruptive loading of reagents in a bodyfluid workstation comprising a plurality of analyzers, including: aninput unit for receiving application information of a first analyzerwhich needs loading of a reagent; a testing unit including a pausingsub-unit, the pausing sub-unit configured for responding to theapplication information, controlling the first analyzer to pause areagent dispensing operation at a determined time, and controlling oneor more other analyzers of the body fluid workstation to continuetesting; a sample loading unit configured for checking one or more testitems performed on samples that are located on every sample rack and atest sequence of every sample rack, determining whether a sample rack isa first sample rack that the first analyzer is testing or will test,and, if so, pausing dispatch of the first sample rack and allowing theone or more other analyzers of the body fluid workstation to continue todispatch sample racks, wherein the test unit includes an adjustingsub-module, the adjusting sub-module configured for adjusting a testsequence of one or more sample racks corresponding to an analyzersubsequent to the first analyzer, and the sample loading unit dispatchesthe one or more sample racks according to the adjusted test sequence.11. The system of claim 10, wherein the pausing sub-unit is configuredfor: determining whether the first analyzer is testing; if so,determining whether the first analyzer meets a pause condition; and whenthe condition is met, controlling the first analyzer to pause dispensinga reagent.
 12. The system of claim 11, wherein the pause condition ismet when all needed reagents have been dispensed into a cuvette if partof reagents have already been added into the cuvette.
 13. The system ofclaim 10, wherein the adjusting sub-module includes: a first check unitconfigured for determining whether the first sample rack needs to betested by a subsequent analyzer of the body fluid workstation after thefirst sample rack is tested by the first analyzer; a test sequencechange unit configured for changing a test sequence of the first samplerack in the subsequent analyzer if the first sample rack needs to betested by the subsequent analyzer, the test sequence of the first samplerack in the subsequent analyzer is adjusted afterward; a sample loadingunit configured for dispatching the first sample rack according to theadjusted test sequence, wherein if a second sample rack is tested in thesubsequent analyzer before the first sample rack is tested in thesubsequent analyzer, the second sample rack is conveyed to a testposition of the subsequent analyzer by a second sample loading trackwhich is different from a first sample loading track for conveying thefirst sample rack; or, a second check unit configured for monitoring atest sequence of a sample rack which is after the first analyzer and,when the first sample rack is going to test, checking a test status ofthe first sample rack in the first analyzer; a test sequence change unitconfigured for changing the test sequence of the first sample rack inthe subsequent analyzer and, when the test of the first sample rack isnot finished in the first analyzer, adjusting the test sequence of thefirst sample rack in the subsequent analyzer afterward; and a sampleloading unit configured for dispatching the first sample rack accordingto the adjusted test sequence, wherein if a second sample rack is testedin the subsequent analyzer before the first sample rack is tested in thesubsequent analyzer, the second sample rack is conveyed to a testposition of the subsequent analyzer by the second sample loading trackwhich is different from a first sample loading track for conveying thefirst sample rack.
 14. The system of claim 10, further comprising: areagent loading unit configured for acquiring one or more parameters ofliquid height of reagent in every analyzer and test items performed onsamples in every analyzer; a residual reagent calculation unitconfigured for calculating a test number of remaining residual reagentsin the first analyzer according to the parameters; and a reagent loadinginform unit configured for comparing the test number that is performedwith the remaining residual reagents in every analyzer to the testnumber of an application, and if the test number of the remainingresidual reagents is less than the test number of the application,notifying a user.
 15. A body fluid workstation including: a sampleloading mechanism including a sample loading track and a sample rackdriving mechanism, the sample loading track configured for holding asample rack, and the sample rack driving mechanism configured for movingthe sample rack to a determined place according to dispatchinginstructions; at least two analyzers having a determined test sequence,each analyzer including a dispensing mechanism, a reagent disk and areaction disk, and an analyzer testing samples of the sample rack whichis conveyed to a determined position; and a loading system configuredfor: responding to application information for loading reagent into afirst analyzer needing reagent, controlling the first analyzer to pausedispensing of the reagent at a determined time, and controlling one ormore other analyzers of the body fluid workstation to continue testing,wherein the loading system is configured to adjust a test sequence ofone or more sample racks in the one or more other analyzers and todispatch the one or more sample racks according to the adjusted testsequence.
 16. The body fluid workstation of claim 15, wherein theloading system: after receiving application information, determineswhether the first analyzer is testing; when the first analyzer istesting, determines whether the first analyzer meets a pause condition;and when the pause condition is met, controls the analyzer correspondingto the application information to pause dispensing of the reagent. 17.The body fluid workstation of claim 16, wherein the pause condition iswhen all needed reagents have been dispensed into a cuvette if a part ofneeded reagents have already been dispensed into the cuvette.
 18. Thebody fluid workstation of claim 15, wherein the loading system: checksone or more test items that are performed on the samples of the samplerack in the first analyzer and a test sequence of every sample rack;determines whether the sample rack is a first sample rack that the firstanalyzer is testing or will test; and generates a dispatchinginstruction to the first sample rack that the first analyzer is testingor will test, wherein the sample loading mechanism pauses dispatching ofthe first sample rack according to the dispatching instruction while thesample racks of the one or more other analyzers continue to dispatch.19. The body fluid workstation of claim 18, wherein the loading systemis configured to determine whether the first sample rack also needs tobe tested by the one or more analyzers of the body fluid workstationand, if so, the loading system changes a test sequence of the firstsample rack in the subsequent analyzer, the test sequence of the firstsample rack in the subsequent analyzer is adjusted afterward.
 20. Thebody fluid workstation of claim 19, further comprising a first sampleloading track and a second sample loading track, wherein the loadingsystem is configured to generate a second dispatching instructionaccording to the adjusted test sequence of the sample rack in thesubsequent analyzer, if a second sample rack is tested in the subsequentanalyzer before the first sample rack is tested in the subsequentanalyzer, controlling the sample loading driving mechanism of the sampleloading mechanism driving the second sample rack by the second sampleloading track which is different from the first sample loading track forconveying the first sample rack.
 21. The body fluid workstation of claim18, wherein the loading system is configured to monitoring a sequence ofsample racks in an analyzer subsequent to the first analyzer; when thesubsequent analyzer is going to test the first sample rack, checkingwhether the first analyzer is still testing; and if the first analyzeris still testing, changing a test sequence of the first sample rack inthe subsequent analyzer, wherein the test sequence of the first samplerack in the subsequent analyzer is adjusted afterward.
 22. The bodyfluid workstation of claim 15, wherein the loading system is configuredfor: acquiring parameters of liquid level of reagent in every analyzerand test items that are performed on the samples in each analyzer;calculating a test number of each residual reagent according to theparameters; and displaying the test number that is performed with theremaining residual reagent in each analyzer.